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Effect of LINE-1 methylation in DM.

Journal: Epigenomes

Article Title: Retrotransposons and Diabetes Mellitus

doi: 10.3390/epigenomes8030035

Figure Lengend Snippet: Effect of LINE-1 methylation in DM.

Article Snippet: Pearce et al., 2012 [ ] , Case-control study , 228 individuals (aged 49–51 years) with risk factors for T2D and CHD , PB samples , Pyrosequencing (PyroMark MD Pyrosequencer Qiagen, UK)/quantification of percentage LINE-1 DNAm , Positive associations between log-transformed LINE-1 DNAm and fasting glucose, TCHOL, TRG, and LDL. Negative association between log-transformed LINE-1 methylation and HDL and HDL:LDL ratio..

Techniques: Methylation, DNA Methylation Assay, Biomarker Discovery, Real-time Polymerase Chain Reaction